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29
2025-10
Literature Sharing: Rapid detection of Ebolavirus using isothermal recombinase-aided amplification
In September of this year, the WHO received an alert from the Ministry of Health of the Democratic Republic of the Congo regarding suspected cases of Ebola Virus Disease (EVD). EVD is a highly fatal infectious disease. Although vaccines have become available, rapid case identification remains crucial for outbreak control, creating a persistent and urgent need for rapid diagnostic methods. Notably, as early as 2024, researchers had already developed an effective solution. The literature shared today introduces a diagnostic method suitable for field detection utilizing Recombinase-Aided Amplification (RAA) technology, which can deliver results within 15 minutes.
17
2025-10
Tier-1 Virus, Tier-1 Solution — QT BIO's Detection Kit for Nipah Virus
The Korea Disease Control and Prevention Agency has announced that starting from September 8, Nipah virus infection will be classified as a Level 1 infectious disease. South Korea has implemented a four-tier classification system for infectious diseases since 2020, with Level 1 being the highest. This is the first time a new disease has been added to the Level 1 category since the four-tier system was introduced in 2020. According to South Korea’s infectious disease classification guidelines, suspected and confirmed cases of Nipah virus will undergo public health management measures, including mandatory reporting, isolation, contact tracing, and epidemiological investigations. The World Health Organization has listed Nipah virus in its priority pathogen list, which includes pathogens with pandemic potential.
19
2025-09
On September 19, 2025, it was reported that the World Health Organization (WHO) had updated its global situation report on the mpox outbreak. Data showed that as of August 31, 2025, a total of 92 countries had reported 38,671 confirmed cases of mpox and 163 deaths, with the majority concentrated in Africa. A collaborative team led by Professor Dan Du from the School of Medicine, Xiamen University and Professor Youzhi Tang from the College of Veterinary Medicine, South China Agricultural University published a paper in Science Bulletin. Based on the trans-cleavage characteristics of Cas13a and Cas12a enzymes in the CRISPR system, this research established one-pot single-target detection methods by combining them with isothermal amplification RAA technology, respectively. Furthermore, these two systems were integrated to create a dual-target detection system.
16
2025-09
The 2025 World Hepatitis Day theme "Let’s Break It Down" emphasizes the need to simplify, scale up, and integrate hepatitis services - vaccination, safe injection practices, harm reduction and especially testing and treatment - into national health systems. HBV remains highly endemic in resource-limited regions like Southeast Asia and Africa, making simple, rapid, and portable field detection methods critical for effective control. This study presents two RAA-based field detection methods capable of completing the entire testing process within 40 minutes.
21
2025-08
African Swine Fever (ASF), caused by the African Swine Fever Virus (ASFV), is a devastating infectious disease affecting domestic and wild pigs. It has significant negative socioeconomic impacts on the global pig industry and food security. The World Organisation for Animal Health (OIE) classifies it as a notifiable disease. To date, there is no effective vaccine or treatment for ASF. Early detection and rapid diagnosis are of critical importance for controlling the spread of ASF.
17
2025-08
According to data from the World Health Organization (WHO), as of 2025, cholera remains a significant public health challenge in multiple regions globally. From January 1 to August 17, 2025, a total of 31 countries reported 409,222 cases of cholera/acute watery diarrhea (AWD), including 4,738 deaths.
06
2025-08
CDC and public health officials in several states are investigating a multistate outbreak of Listeria infections linked to ready-to-eat foods made by Fresh & Ready Foods LLC. Foods include items like sandwiches and protein snacks. (Source: CDC). Listeria monocytogenes is a highly lethal foodborne pathogen that contaminates dairy products, meats, and other foods, causing sepsis, meningitis, and a mortality rate of 27%–44%.
05
2025-06
This year, the theme of World Food Safety Day is science in action. As innovation determines the future, science and technology are crucial in ensuring food safety. Rapid detection of foodborne pathogens has always been a key link in food safety prevention and control. As the most common pathogen causing food poisoning worldwide, the innovation of Salmonella detection technology has significant public health implications. This study introduces a recombinase-aided isothermal nucleic acid amplification method for rapid Salmonella detection that can complete the entire testing process within 20 minutes.
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